Abstract
Sethoxydim, a commercially available cyclohexanedione class herbicide by targeting the enzymatic activity of acetyl-coenzyme A carboxylase, has been found to moderately inhibit the activity of 4-hydroxyphenylpyruvate dioxygenase, a key enzyme in the biosynthesis of plastoquinones and tocopherols in plants.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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4-Hydroxyphenylpyruvate Dioxygenase / antagonists & inhibitors*
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Acetyl-CoA Carboxylase / antagonists & inhibitors*
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Animals
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Cyclohexanones / pharmacology*
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Enzyme Inhibitors / pharmacology*
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Herbicides / pharmacology*
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Liver / drug effects
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Liver / enzymology
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Swine
Substances
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Cyclohexanones
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Enzyme Inhibitors
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Herbicides
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sethoxydim
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4-Hydroxyphenylpyruvate Dioxygenase
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Acetyl-CoA Carboxylase